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Drug ReportsFlorbetapir (18f)
Florbetapir f 18
Amyvid (florbetapir f 18) is a small molecule pharmaceutical. Florbetapir f 18 was first approved as Amyvid on 2012-04-06. It has been approved in Europe to treat radionuclide imaging.
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Therapeutic Areas
Therapeutic Area
MeSH
diagnosisD003933
Trade Name
FDA
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Drug Products
FDA
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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FDA
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Brand Name
Status
Last Update
amyvidNew Drug Application2024-11-13
Indications
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FDA Information
Florbetapir F-18, Amyvid, Avid Radiopharms Inc
76870522027-04-30DS, DP
85069292027-04-30DS, DPU-1423
ATC Codes
V: Various drug classes in atc
V09: Diagnostic radiopharmaceuticals
V09A: Central nervous system diagnostic radiopharmaceuticals
V09AX: Other central nervous system diagnostic radiopharmaceuticals in atc
V09AX05: Florbetapir (18f)
HCPCS
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Clinical
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Drug
General
Drug common nameFlorbetapir f 18
INNflorbetapir (18f)
Description
Florbetapir F-18 is an aromatic ether consisting of a pyridine ring substituted at position 2 by a 2-{2-[2-((18)F)fluoroethoxy]ethoxy}ethoxy group and at position 5 and a 2-(4-methylaminophenyl)vinyl group. A positron emission tomography imaging ligand for the detection of amyloid aggregation associated with Alzheimer disease. It has a role as a radioactive imaging agent. It is an organofluorine compound, a member of pyridines, an aromatic ether, a (18)F radiopharmaceutical and a substituted aniline.
Classification
Small molecule
Drug class
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CNc1ccc(/C=C/c2ccc(OCCOCCOCC[18F])nc2)cc1
Identifiers
PDB
CAS-ID956103-76-7
RxCUI
ChEMBL IDCHEMBL1774461
ChEBI ID66880
PubChem CID24822371
DrugBank
UNII ID6W15Z5R0RU (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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